The weekly ACC Sport competition runs alongside the House Sport program during timetabled periods 5 and 6 on Tuesday for Year 9 and 10 students, Wednesday for Year 11 and 12 students and Thursday for Year 7 and 8 students. The weekly sports vary across the year and are played per term.
In Term 1, Year 11 and 12 students compete in Cricket, Tennis and Volleyball. In Term 2 all year levels have the opportunity to participate in Australian Rules Football, Badminton and Soccer. Basketball, Hockey and Table Tennis are offered to all students in Term 3. While students in Year 7 to 10 can represent Mazenod in Cricket, Tennis or Volleyball in Term 4.
Mazenod has achieved success in all disciplines, but lead the ACC in Volleyball, Table Tennis, Soccer, and Badminton.